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  Wednesday, December 9, 2015

World's First Ibuprofen Patch: University of Warwick sets world record (VIDEO)

COVENTRY, UK -- Researchers at the University of Warwick have worked with Coventry-based Medherant , a Warwick spinout company, to produce and patent the World's first ever ibuprofen patch delivering the drug directly through skin to exactly where it is needed at a consistent dose rate,
setting the new world record for the World's First Ibuprofen Patch, according to the World Record Academy .
 Researchers at the University of Warwick have worked with Coventry-based Medherant, a Warwick spinout company, to produce and patent the World's first ever ibuprofen patch delivering the drug directly through skin to exactly where it is needed at a consistent dose rate.
  Photo: Researchers at the University of Warwick have worked with Coventry-based Medherant, a Warwick spinout company, to produce and patent the World's first ever ibuprofen patch delivering the drug directly through skin to exactly where it is needed at a consistent dose rate. ( enlarge photo )

The Guinness World Records' record for the most expired medicine collected in 24 hours (multiple locations) is 1,072.6 kg (2,364.68 pounds) and was achieved by Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. (China), in Guangzhou, Guangdong, China, on 11 March 2014. The medicine was collected in 10 different locations.

  Guinness World Records also recognized the world record for the most push ups on medicine balls in one minute; it is 68, achieved by Mohammad Hassaan Butt (Pakistan) in Karachi, Pakistan, on 7 June 2015.

   They have invented a transparent adhesive patch that can consistently deliver a prolonged high dose of the painkiller ibuprofen directly through the skin.

   The University of Warwick researchers and Medherant have found a way to incoporate significant amounts of the drug (up to 30% weight) into the polymer matrix that sticks the patch to the patient's skin with the drug then being delivered at a steady rate over up to 12 hours.

   This opens the way for the development of a range of novel long-acting over-the-counter pain relief products which can be used to treat common painful conditions like chronic back pain, neuralgia and arthritis without the need to take potentially damaging doses of the drug orally.
   Although there are a number of popular ibuprofen gels available these make it difficult to control dosage and are inconvenient to apply.

    The key features of Medherant 's new patch technology are:
     # The patch remains highly tacky and thus adheres well to skin even when the drug load reaches levels as high as 30% of the weight/volume of the patch. The drug load made possible by this new technology can be 5 -10 times than that found in some currently used medical patches and gels.      # High drug load and a consistent drug release profile means the Medherant patches out-perform other patches and gels in their ability to deliver a consistent and significant dose of drug over a prolonged time from a small patch.
     # It is a cosmetically pleasing transparent design with stronger adhesion than other commercial products – remaining stuck over its time of action but easy and comfortable to remove.

    Nigel Davis CEO of Medherant said: "Our transdermal patch technology expands the range of drugs that can be delivered via skin patches and can significantly increase drug loading capabilities, whilst retaining adhesion and being thin and flexible. Thus our patches provide a better experience for patients, enhance safety and deliver increased efficacy, which will lead to economic benefits to the healthcare system."


     Related world records:  
Most people in a CPR relay: University of Manchester breaks Guinness World Records record (VIDEO)

Longest line of people using stethoscopes: Florida breaks Guinness World Records record

Oldest hip replacement patient: Gladys Hooper breaks Guinness World Records record (VIDEO )

World's first skull and scalp transplant: Texas doctors set world record (VIDEO)

Most Iris observations and analysis: Lee Nam-han sets world record (VIDEO)


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